PRP: platelet rich plasma

Platelet rich plasma injections (PRP injections)

원심분리기로 환자의 혈액에서 혈소판만을 추출하여 운동으로 손상된 인대등의 신체조직에 주사하여 회복을 촉진시키는 방법. 

PRP injections are a new medical technology used in the treatment of many sporting injuries. This website aims to provide information about this therapy and where it can be performed.

The field of sports medicine is advancing at a rapid pace and is encouraging millions of people from athletes to the general population to participate in regular activity to stay healthy and active (1). However this increase in physical activity has also seen an increase in musculoskeletal injuries. The World Health Organisation has recently recognised that musculoskeletal injuries affect hundreds of millions of people worldwide and are the most common cause of severe long term pain and physical disability (2). In Australia alone, there are almost 4 cases of medically treated sporting injuries per 100 persons (3).

Soft tissue injuries which include ligament and tendons represent up to 45% of all musculoskeletal injuries (4,5). The increasing participation in sporting activities coupled together with improved modern imaging techniques such as MRI and high resolution ultrasound have helped sports medicine practitioners to better understand these injuries (6).

Platelets are small discoid cells with a life span of about 7-10 days. Inside platelets contain granules which contain clotting and growth factors. During the healing process, the platelets are activated and aggregate together. They then release the granules which contain growth factors which stimulate the inflammatory cascade and healing process (2).

Blood typically contains 6% platelets whereas PRP has a significantly increased supra-physiological platelet concentration. Although this level can vary depending on the method of extraction and equipment, studies have shown that clinical benefit can be obtained if the PRP used has an increased platelet concentration of 4x greater than normal blood (3).

References
1. Sánchez M, Anitua E, Orive G, Mujika I, Andia I. Platelet-rich therapies in the treatment of orthopaedic sport injuries. Sports Med. 2009;39(5):345-54.
2. Woolf AD, Pfleyer B. Burdon of major musculoskeletal conditions. Bull World Health Organ. 2003;81:646–56.
3. Cassel EP, Finch CF, Stathakis VZ. Epidemiology of medically treated sport and active recreation injuries in the Latrobe Valley, Victoria, Australia. Br J Sports Med 20032; 37: 405-9.
4. Anitua M, Sánchez E, Nurden A, Nurden P, Orive G, And ́ıa I. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol. 2006;24(5):227–34.
5. Praemer AF. Musculoskeletal conditions in the United States. 2nd ed. Rosemont: American Academy of Orthopaedic Surgeons; 1999.
6. Sampson S, Gerhardt M, Mandelbaum B. Platelet rich plasma injection grafts for musculoskeletal injuries: a review. Curr Rev Musculoskelet Med. 2008 Dec;1(3-4):165-74.

ref: http://www.prpinjection.com.au/index.html